Why the study?
Does permanent cardiac pacing prevent syncope and seizures in children with frequent severe neurally mediated syncope?
Population
12 children aged 2-14 years with frequent episodes of reflex anoxic seizures and a recorded prolonged…
Comparison
Dual chamber pacing with rate drop response and… vs Sensing only programmed for a four month period.
Design
RCT, Allocated to one of the six possible sequences of these modes, according…
Follow-up
Four month periods for each mode
Authors
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Supports pacing for severe neurally mediated syncope in children; extends adult RCT evidence to pediatrics.
Does permanent cardiac pacing prevent syncope and seizures in children with frequent severe neurally mediated syncope?
Permanent pacing (both VVI and DDD) effectively reduces syncopal episodes in children with severe neurally mediated syncope, with DDD being superior for preventing presyncopal symptoms.
McLeod et al. (1999) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: