April 1, 1996Acta Physiologica Scandinavica

Central command increases cardiac output during static exercise in humans

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Population

10 human subjects

Comparison

Static two-leg exercise vs External compression of the legs and…

Design

Other

Authors

JWJohn WilliamsonCooper University Hospital HOH. L. OlesenCopenhagen University Hospital FPFrank PottFrederiksberg Hospital

Discussion

Member takes

Implication

Should not yet change exercise testing protocols; hypothesis-generating for central command versus reflex contributions in dynamic or clinical settings.

Structured PICO

Population

10 human subjects

Intervention

Static two-leg exercise

Comparator

External compression of the legs (80 mmHg) and post-exercise muscle ischaemia

Outcome

Hemodynamic responses including mean arterial pressure, heart rate, cardiac output, and total peripheral resistancesurrogate

Central command during static exercise specifically increases heart rate and cardiac output, whereas mechanical and metabolic reflexes primarily mediate increases in peripheral resistance.

Cite This Study

Williamson et al. (1996) studied this question.

synapsesocial.com/papers/6a7a735c8a3ae1c74232cb58 https://doi.org/10.1046/j.1365-201x.1996.472186000.x

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Implication

Should not yet change exercise testing protocols; hypothesis-generating for central command versus reflex contributions in dynamic or clinical settings.