October 1, 1997Clinical Science

Mutations at the Lipoprotein Lipase Gene Locus in Subjects with Diabetes Mellitus, Obesity and Lipaemia

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Population

18 patients with diabetes mellitus, obesity, and severe hypertriglyceridaemia

Design

Case_series

Authors

QZQiuping ZhangFujian Medical University ECE. CavalleroCentre Hospitalier Universitaire Henri-Mondor MHMichael M. HoffmannRoskamp Institute

Discussion

Member takes

Implication

Does not warrant changes in hypertriglyceridemia management; hypothesis-generating for LPL contribution and requires larger validation.

Structured PICO

Population

18 patients with diabetes mellitus, obesity, and severe hypertriglyceridaemia

Outcome

Genetic variants at the lipoprotein lipase gene locussurrogate

Genetic variants at the lipoprotein lipase locus are common in patients with diabetes, obesity, and severe hypertriglyceridaemia, potentially contributing to impaired triacylglycerol clearance.

Cite This Study

Zhang et al. (1997) studied this question.

synapsesocial.com/papers/6a7a73851ba4614d7ff3e98e https://doi.org/10.1042/cs0930335

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Mutations at the Lipoprotein Lipase Gene Locus in Subjects with Diabetes Mellitus, Obesity and Lipaemia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Mutations at the Lipoprotein Lipase Gene Locus in Subjects with Diabetes Mellitus, Obesity and Lipaemia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider