Why the study?
Does facial cooling increase central aortic pressure, arterial stiffness, and wave reflection in healthy subjects?
Population
12 healthy subjects (age 23 +/- 3 yr; 6 men, 6 women)
Comparison
Facial cooling trial using a 0 degrees C gel pack vs Control trial consisting of supine rest
Follow-up
7 minutes
Authors
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May underlie cold-related CV events via stiffness changes; hypothesis-generating in healthy subjects, needs patient confirmation.
Does facial cooling increase central aortic pressure, arterial stiffness, and wave reflection in healthy subjects?
Facial cooling increases wave reflection and central systolic pressure, providing a potential hemodynamic mechanism for the increased incidence of cardiovascular events during cold exposure.
Edwards et al. (2008) studied this question.
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