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Epi-fluorescence video microscopy, digital image processing, and photodiode measurements were used to visualize and analyze mural thrombogenesis, the initial stages of blood platelet adhesion to and aggregation on a surface. This technique permitted real-time visualization, high-resolution, quantitative, off-line measurement of the growth of individual thrombi and high-resolution, quantitative, end-point measurement of the accumulation of platelets as a function of position on the surface.
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Hubbell et al. (1986) studied this question.
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