This case report highlights an atypical extended survival in a patient with recurrent metastatic synovial sarcoma treated with surgery and chemotherapy.
Highlights unusual breast/pulmonary metastases in synovial sarcoma; leaves open optimal management in recurrent metastatic disease.
Synovial sarcoma is a mesenchymal tumour with partial epithelial differentiation. About 85-90% of SS occur in the extremities. We present a case of a 44-year-old woman diagnosed with recurrent synovial sarcoma with breast and pulmonary nodules. The primary treatment for synovial sarcoma is wide surgical excision, while chemotherapy is reserved for metastatic cases. In the first-line metastatic setting, combination treatment with adriamycin and ifosfamide is administered. Despite the unfavourable prognosis, the patient's extended survival is fortunately not the typical outcome.
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Khanal et al. (2024) studied this question.
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