Why the study?
Does the clustering of multiple risk factors increase the risk of hypertension and correlate with blood pressure levels in a screened cohort?
Population
9,914 individuals screened in Okinawa, Japan in 1997, including 2,465 hypertensive and 7,449…
Comparison
Clustering of up to five risk factors vs Subjects with fewer or zero risk factors
Design
Cross-sectional
Authors
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Hypothesis-generating for multifactorial prevention; prospective studies needed to confirm causality and guide practice.
Does the clustering of multiple risk factors increase the risk of hypertension and correlate with blood pressure levels in a screened cohort?
The accumulation of multiple cardiovascular risk factors is strongly and dose-dependently associated with the prevalence of hypertension and higher blood pressure levels even in non-hypertensive individuals.
Tozawa et al. (2000) studied this question.
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