This first reported case of ticagrelor use during human pregnancy resulted in an uneventful maternal course but was associated with a small-for-gestational-age neonate and subclinical decidual hemorrhage.
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Ticagrelor use throughout pregnancy appeared uneventful in one case; leaves open questions on SGA risk and requires larger prospective studies.
Ticagrelor was daily administered throughout pregnancy to a 37-year-old pregnant woman until 36 weeks of gestation. The patient, with Behçet disease, suffered from a non-ST elevation myocardial infarction 4 months before conception, possibly related to hypertension and tobacco abuse. Pregnancy and postpartum periods were uneventful. She delivered a healthy but small-for-gestational-age term neonate.
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Verbruggen et al. (2015) studied this question.
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