Why the study?
The study was conducted to investigate fluctuations of organized activity during ventricular fibrillation in the canine heart.
Ventricular fibrillation in the canine heart exhibits stationary fluctuations of organized activity that maintain the stability of its structure over a 30-minute period.
Animal VF data warrant no clinical change; leaves open human translation of arrhythmia organization.
The aim of the paper was to study fluctuations of organized activity of ventricular fibrillation of the canine heart. To solve the aim we performed frequency-amplitude analysis of the ventricular electrogram during fibrillation using the Fast Fourier Transform at 30 frequencies in the range of 0.5–15 Hz: 0.5, 1, 1.5, …, 15 Hz. Ventricular fibrillation was characterized by fluctuations of organized activity as evidenced by fluctuations of frequency and amplitude of dominating oscillations when analysing 1-second intervals of fibrillation. Fluctuations of organized activity was maintained in stationary mode as evidenced by disappearance of fluctuations of frequency and amplitude when averaging 1-second values of frequency and amplitude of oscillations in the 3-minute intervals of fibrillation. Stationary fluctuations maintain stability of organized structure of fibrillation during the 30-minute perfusion of the heart.
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Gurianov et al. (2022) studied this question.
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