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Evaluate the impact of Limosilactobacillus reuteri DSM 17938 on diaper dermatitis incidence in antibiotic-treated neonates.

August 11, 2026ChildrenOpen Access

Probiotic Supplementation to Prevent Diaper Dermatitis in Antibiotic-Treated Neonates: Secondary Analysis of a Randomised Controlled Trial

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Evaluate the impact of Limosilactobacillus reuteri DSM 17938 on diaper dermatitis incidence in antibiotic-treated neonates.
Secondary analysis of a randomised, double-blind, placebo-controlled trial
89 term neonates treated with antibiotics during the first 3 weeks of life
Comparison of DD incidence between probiotic and placebo groups over 6 weeks.
24 (28%) infants developed diaper dermatitis, with 6 (25%) having fungal DD.
No significant difference in DD incidence between the probiotic (30%) and placebo (25%) groups.
Probiotic supplementation did not significantly alter gut microbiota composition or diversity.

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Randomized trial evaluates probiotic effects on diaper dermatitis in neonates, suggesting limited benefits.

Železnik et al. (2026) studied this question.

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