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March 31, 2025Annals of Internal MedicineOpen Access

Patient Navigation to Improve Colonoscopy Completion After an Abnormal Stool Test Result

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Authors

GCGloria D. CoronadoAPAmanda F. PetrikJTJamie H. Thompson

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Overview

Randomized trial finds telephone-based patient navigation increases follow-up colonoscopy completion in adults with abnormal stool tests, supporting targeted outreach for colorectal care.

Key Points

  • To determine whether a telephone-based patient navigation program delivered to adults with an abnormal stool test result increases follow-up colonoscopy completion at one year.
  • Randomized controlled trial (ClinicalTrials.gov: NCT03925883) conducted across 32 clinics in Washington state enrolling 985 adults aged 50 to 75 years with an abnormal fecal test result in the prior month.
  • Participants were assigned to usual care or a 6-topic, telephone-delivered patient navigation program administered by bilingual (English and Spanish) clinical staff.
  • The primary outcome was follow-up colonoscopy completion at 1 year assessed in 967 participants via intention-to-treat analysis (479 in patient navigation, 488 in usual care).
  • Follow-up colonoscopy completion at 1 year was significantly higher in the patient navigation arm than in usual care (55.1% vs. 42.1%; risk difference, 13.0 percentage points [95% CI, 6.5 to 19.4 percentage points]).
  • The intervention benefit was not moderated by participants' baseline probability of completing a colonoscopy without navigation.

Cite This Study

Coronado et al. (2025) studied this question.

synapsesocial.com/papers/6a7ad2ebdd2e05b79c321c7ehttps://doi.org/10.7326/annals-24-01885
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acceptability of Patient Navigation to Promote Follow-up Colonoscopy2024
  2. 2Navigation activities in an organized colorectal cancer screening program improve follow-up colonoscopy completion2026 · 1 citations
  3. 3Adaptations to a patient navigation program for follow‐up colonoscopy in rural primary care practices2024 · 1 citations
  4. 4Multilevel challenges and adaptations to patient navigation programs for colorectal cancer screening and follow‐up: Findings from the Accelerating Colorectal Cancer Screening and follow‐up through Implementation Science consortium2025
  5. 5The COMPLETE-CRC Screening Initiative: Increasing Colonoscopy Completion After Positive Stool-Based Colorectal Cancer Screening2026 · 1 citations