What question did this study set out to answer?

To determine the incidence, clinical manifestations, and mortality of respiratory syncytial virus infection among hospitalized adult patients with leukemia.

August 1, 1995Clinical Infectious Diseases

Respiratory Syncytial Virus Pneumonia in Hospitalized Adult Patients with Leukemia

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Authors

EWEstella WhimbeyUniversity of Washington RCR. B. CouchAustralian National University JEJanet A. EnglundRutgers, The State University of New Jersey

Discussion

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Implication

Prospective study reveals high rates of fatal pneumonia from respiratory syncytial virus in adult leukemia patients, highlighting the threat of seasonal viral infections in myelosuppressed hosts.

Key Points

To determine the incidence, clinical manifestations, and mortality of respiratory syncytial virus infection among hospitalized adult patients with leukemia.
Prospective 1-year surveillance (November 1993 to October 1994) of all hospitalized adult leukemia patients at a single comprehensive cancer center.
Viral isolation performed on hospitalized leukemia patients presenting with acute respiratory illness during a 19-week community outbreak period.
Respiratory syncytial virus was isolated from 9 of 87 leukemia patients (10%) who developed acute respiratory illness during the community prevalence window.
Pneumonia complicated the viral infection in 6 of 8 patients (75%) who had profound chemotherapy-induced myelosuppression.
Infection-related mortality reached 83% among myelosuppressed patients who developed respiratory syncytial virus pneumonia.

Cite This Study

Whimbey et al. (1995) studied this question.

synapsesocial.com/papers/6a7aef5006bbdce3610226c2 https://doi.org/10.1093/clinids/21.2.376

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August 1, 1995Clinical Infectious Diseases

Respiratory Syncytial Virus Pneumonia in Hospitalized Adult Patients with Leukemia

View Full Paper

Ask AI

Bookmark

Authors

EWEstella WhimbeyUniversity of Washington RCR. B. CouchAustralian National University JEJanet A. EnglundRutgers, The State University of New Jersey

Discussion

Member takes

Implication

Prospective study reveals high rates of fatal pneumonia from respiratory syncytial virus in adult leukemia patients, highlighting the threat of seasonal viral infections in myelosuppressed hosts.

Key Points

To determine the incidence, clinical manifestations, and mortality of respiratory syncytial virus infection among hospitalized adult patients with leukemia.
Prospective 1-year surveillance (November 1993 to October 1994) of all hospitalized adult leukemia patients at a single comprehensive cancer center.
Viral isolation performed on hospitalized leukemia patients presenting with acute respiratory illness during a 19-week community outbreak period.
Respiratory syncytial virus was isolated from 9 of 87 leukemia patients (10%) who developed acute respiratory illness during the community prevalence window.
Pneumonia complicated the viral infection in 6 of 8 patients (75%) who had profound chemotherapy-induced myelosuppression.
Infection-related mortality reached 83% among myelosuppressed patients who developed respiratory syncytial virus pneumonia.

Cite This Study

Whimbey et al. (1995) studied this question.

synapsesocial.com/papers/6a7aef5006bbdce3610226c2 https://doi.org/10.1093/clinids/21.2.376

Also Consider

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