Key result
Application of the 2017 ACC/AHA blood pressure guidelines to a Canadian primary care cohort increased the prevalence of hypertension from 24.2% to 42.4%.
Why the study?
The 2017 ACC/AHA guidelines redefined hypertension using lower diagnostic thresholds and treatment targets, prompting evaluation of their potential impact on hypertension diagnosis, treatment, and control in Canadian primary care.
Does the application of the 2017 ACC/AHA blood pressure guidelines increase the prevalence of hypertension in Canadian adults?
Cross-Sectional (n=594,492)
Yes
Does the application of the 2017 ACC/AHA blood pressure guidelines increase the prevalence of hypertension in Canadian adults?
Absolute Event Rate: 42.4% vs 24.2%
Adoption of the 2017 ACC/AHA blood pressure guidelines in Canada would nearly double the prevalence of hypertension, primarily affecting younger, lower-risk individuals.
May increase diagnosed hypertension prevalence in Canadian primary care; leaves open whether lower targets improve outcomes.
Importance: The 2017 American College of Cardiology and American Heart Association (ACC/AHA) blood pressure (BP) guidelines redefined hypertension using a BP threshold of 130/80 mm Hg or greater and applied a treatment target of less than 130/80 mm Hg. Objective: To evaluate the potential change in the diagnosis, treatment, and control of hypertension in a Canadian cohort of patients with hypertension attending primary care practices using the ACC/AHA guidelines. Design, Setting, and Participants: This cross-sectional study used primary care practices across Canada electronic medical record data from the Canadian Primary Care Sentinel Surveillance Network, extracted as of June 30, 2015. Adults with at least 1 primary care encounter in the previous 2 years (July 1, 2013, to June 30, 2015) were included in the study. Those with current hypertension were identified using a validated definition consisting of diagnoses, billing codes, and/or antihypertensive medication from within the primary care electronic medical record. Data analysis was conducted from December 2017 to July 2018. Main Outcomes and Measures: Proportion of individuals with a diagnosis of hypertension, prescribed antihypertensive medication, and meeting treatment BP targets. Results: Of the 594 492 Canadian participants included in the study, 144 348 (24.2%) had hypertension (45.6% male; mean [SD] age, 65.5 [14.5] years). On applying the ACC/AHA guidelines, 252 279 individuals (42.4%) were considered hypertensive and half (51.0%; 95% CI, 50.8%-51.2%) were prescribed an antihypertensive medication. Individuals who were not previously considered to have hypertension but were reclassified as having elevated BP using the lower cutoff of 130/80 mm Hg or greater tended to be younger and were at lower cardiovascular risk. There was a shift toward more individuals requiring antihypertensive treatment, particularly in the lower-risk categories. The crude prevalence of hypertension increased from 13.3% to 32.0% in those aged 18 to 64 years, and of those aged 65 years and older, 16.6% more individuals were reclassified as having hypertension (from 55.2% to 71.8%). Only 12.3% of those who were considered at high risk were reclassified as hypertensive. Conclusions and Relevance: Adoption of the ACC/AHA BP guidelines would result in a near doubling in the prevalence of hypertension in Canada. The changes would largely affect individuals who are younger and at low to moderate cardiovascular risk.
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Garies et al. (2019) conducted a cross-sectional in Hypertension (n=594,492). 2017 ACC/AHA blood pressure guidelines vs. Previous hypertension definition was evaluated on Proportion of individuals with a diagnosis of hypertension. Application of the 2017 ACC/AHA blood pressure guidelines to a Canadian primary care cohort increased the prevalence of hypertension from 24.2% to 42.4%.
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