Key result
A high SYNTAX score II was significantly associated with the development of new-onset atrial fibrillation in patients with NSTE-ACS undergoing PCI (P<0.001).
Why the study?
New-onset atrial fibrillation is associated with poor outcomes in ACS, prompting investigation into its relationship with CAD severity using the SYNTAX score and SYNTAX score II in patients with NSTE-ACS undergoing PCI.
Does the SYNTAX score II predict the development of new-onset atrial fibrillation in patients with NSTE-ACS undergoing PCI?
Cohort (n=662)
Does the SYNTAX score II predict the development of new-onset atrial fibrillation in patients with NSTE-ACS undergoing PCI?
p-value: p=<.001
A high SYNTAX score II is significantly associated with the development of new-onset atrial fibrillation in patients with NSTE-ACS undergoing PCI.
May flag greater CAD complexity in NSTE-ACS; leaves open incremental value over SYNTAX scores for risk stratification.
New-onset atrial fibrillation (NOAF) has been associated with poor outcome in patients with acute coronary syndromes (ACSs). The objective of this study was to investigate the relationship between the development of NOAF and severity of coronary artery disease using the SYNTAX score (SS) and SYNTAX score II (SSII) in patients with non-ST-segment elevation ACS (NSTE-ACS) who were treated with percutaneous coronary intervention (PCI). A total of 662 patients with NSTE-ACS were consecutively enrolled. The incidence of NOAF was 11.4% among the patients with NSTE-ACS. Mean age was significantly higher in NOAF group ( P = .011). White blood cell count, peak troponin I, high sensitivity C-reactive protein, uric acid, left atrial volume index, and ratio between early mitral inflow velocity and mitral annular early diastolic velocity were significantly higher in NOAF group (respectively, P = .024, P = .017, P = .002, P = .009, P = .025, P < .001, and P < .001). The hemoglobin, ejection fraction, and post PCI thrombolysis in myocardial infarction grade <3 were significantly lower in NOAF group ( P = 001, P = .010, P = .038). The SS and SSII were significantly higher in NOAF group (all P < .001). According to the results of multivariate logistic regression analysis, the SSII was correlated with NOAF ( P < .001) in the study groups. We demonstrated that high SSII is significantly associated with NOAF.
No takes yet. Share an insight, caveat, or question.
Yıldırım et al. (2019) conducted a cohort in Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) (n=662). SYNTAX score II (SSII) was evaluated on New-onset atrial fibrillation (NOAF) (p=<.001). A high SYNTAX score II was significantly associated with the development of new-onset atrial fibrillation in patients with NSTE-ACS undergoing PCI (P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: