Key result
Transapical TAVI using the JenaValve prosthesis was feasible and safe in two patients with pre-existing mitral valve prostheses, resulting in no paravalvular leakage up to 2.8 years post-operatively.
Why the study?
Does transapical TAVI using a JenaValve prosthesis improve outcomes in patients with severe aortic stenosis and pre-existing mitral valve prostheses?
Case Report (n=2)
No
Does transapical TAVI using a JenaValve prosthesis improve outcomes in patients with severe aortic stenosis and pre-existing mitral valve prostheses?
Transapical TAVI using the JenaValve device is a feasible and safe alternative to conventional aortic valve replacement in patients with pre-existing mitral prostheses.
BACKGROUND: Transcatheter aortic valve implantation (TAVI) has proven to be a valid option for patients with severe aortic stenosis who are at high perioperative risk, particularly in patients with previous cardiac surgery. Several patients with previous mitral valve surgery were reported to have been successfully treated with TAVI. CASE PRESENTATION: Two patients, one with mechanical and one with biological mitral valve prosthesis, presented with symptomatic severe aortic stenosis. After discussion among our multidisciplinary heart team transapical approach and a JenaValve™ prosthesis was used for TAVI. Main reasons were to decrease the perioperative risk, avoid a re-opening of the chest via median sternotomy, and discuss the possible superiority of the JenaValve™ device due to its design. The patients were successfully treated and discharged on the 11th and 14th post-operative day, respectively. Echocardiographic follow up before discharge and up to 2.8 years post-operatively showed excellent results. CONCLUSIONS: In conclusion, TAVI in patients with preexisting mitral prostheses-mechanical or biological-is feasible, safe, and effective and offers a valid alternative to conventional aortic valve replacement in this particular re-operation scenario. The JenaValve™ device does not interact with the mitral prosthesis and offers therefore due to its unique design a potential advantage.
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Wachter et al. (2016) conducted a case report in Severe aortic stenosis with pre-existing mitral valve prosthesis (n=2). Transapical transcatheter aortic valve implantation (TAVI) using JenaValve prosthesis was evaluated on Procedural success and echocardiographic outcomes. Transapical TAVI using the JenaValve prosthesis was feasible and safe in two patients with pre-existing mitral valve prostheses, resulting in no paravalvular leakage up to 2.8 years post-operatively.
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