Key result
Peritoneal dialysis was not associated with a significantly different risk of new-onset atrial fibrillation compared to haemodialysis in patients with end-stage renal disease (HR 0.94).
Why the study?
Does haemodialysis compared to peritoneal dialysis affect the incidence of new-onset atrial fibrillation and clinical outcomes in adult end-stage renal disease patients?
Population
1,130 adult patients who initiated dialysis between 2002 and 2015 in Southern Israel, excluding those with…
Comparison
Haemodialysis (HD) vs Peritoneal dialysis (PD)
Design
Cohort
Follow-up
mean 39.7 months
Authors
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AF links to higher HF and mortality but not stroke similarly in HD and PD; leaves open modality-specific effects on incidence.
Cohort (n=1,130)
No
Does haemodialysis compared to peritoneal dialysis affect the incidence of new-onset atrial fibrillation and clinical outcomes in adult end-stage renal disease patients?
Hazard Ratio: 0.94 (95% CI 0.88–1.01)
Absolute Event Rate: 13.7% vs 17.3%
p-value: p=0.08
Atrial fibrillation is common in dialysis patients irrespective of modality, with older age and enlarged left atrium being the primary risk factors, and is associated with increased mortality.
Abuhasira et al. (2018) conducted a cohort in End-stage renal disease (n=1,130). Peritoneal dialysis vs. Haemodialysis was evaluated on New-onset atrial fibrillation (HR 0.94, 95% CI 0.88-1.01, p=0.08). Peritoneal dialysis was not associated with a significantly different risk of new-onset atrial fibrillation compared to haemodialysis in patients with end-stage renal disease (HR 0.94).
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