What question did this study set out to answer?

To develop and evaluate catalytic systems using N-hydroxyphthalimide (NHPI) for the aerobic oxidation and radical functionalization of hydrocarbons under mild conditions.

July 1, 2001Advanced Synthesis & Catalysis

Innovation of Hydrocarbon Oxidation with Molecular Oxygen and Related Reactions

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Authors

YIYasutaka IshiiKansai University SSSatoshi SakaguchiKansai University TITakahiro IwahamaKansai University

Discussion

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Implication

Methodological study demonstrates aerobic hydrocarbon oxidation using N-hydroxyphthalimide catalysis under mild conditions, highlighting scalable pathways for industrial organic synthesis.

Key Points

To develop and evaluate catalytic systems using N-hydroxyphthalimide (NHPI) for the aerobic oxidation and radical functionalization of hydrocarbons under mild conditions.
Combined N-hydroxyphthalimide (NHPI) with transition metals (including cobalt and manganese) and molecular oxygen or air to generate catalytic carbon radicals.
Tested oxidation and functionalization across diverse substrates including alkanes, alkylbenzenes, xylenes, methylpyridines, alcohols, alkynes, and alkenes under mild temperature and pressure.
Investigated extended reactions including alkene epoxidation, carbon monoxide carboxylation, nitrogen dioxide nitration, sulfur dioxide sulfonation, and carbon-carbon bond formations.
Oxidized alkanes to alcohols, ketones, and dicarboxylic acids, and converted xylenes and methylpyridines to phthalic and pyridinecarboxylic acids in good yields.
Achieved selective alkene epoxidation and transformation of alcohols to carbonyl compounds and alkynes to ynones using in situ-generated peroxides.
Demonstrated catalytic alkane carboxylation with carbon monoxide, nitration with nitrogen dioxide, sulfonation with sulfur dioxide, and carbon-carbon bond construction with alkenes.

Cite This Study

Ishii et al. (2001) studied this question.

synapsesocial.com/papers/6a7b4cec5968508e56f3f9ff https://doi.org/10.1002/1615-4169(200107)343:5<393::aid-adsc393>3.0.co;2-k

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July 1, 2001Advanced Synthesis & Catalysis

Innovation of Hydrocarbon Oxidation with Molecular Oxygen and Related Reactions

View Full Paper

Ask AI

Bookmark

Authors

YIYasutaka IshiiKansai University SSSatoshi SakaguchiKansai University TITakahiro IwahamaKansai University

Discussion

Member takes

Implication

Methodological study demonstrates aerobic hydrocarbon oxidation using N-hydroxyphthalimide catalysis under mild conditions, highlighting scalable pathways for industrial organic synthesis.

Key Points

To develop and evaluate catalytic systems using N-hydroxyphthalimide (NHPI) for the aerobic oxidation and radical functionalization of hydrocarbons under mild conditions.
Combined N-hydroxyphthalimide (NHPI) with transition metals (including cobalt and manganese) and molecular oxygen or air to generate catalytic carbon radicals.
Tested oxidation and functionalization across diverse substrates including alkanes, alkylbenzenes, xylenes, methylpyridines, alcohols, alkynes, and alkenes under mild temperature and pressure.
Investigated extended reactions including alkene epoxidation, carbon monoxide carboxylation, nitrogen dioxide nitration, sulfur dioxide sulfonation, and carbon-carbon bond formations.
Oxidized alkanes to alcohols, ketones, and dicarboxylic acids, and converted xylenes and methylpyridines to phthalic and pyridinecarboxylic acids in good yields.
Achieved selective alkene epoxidation and transformation of alcohols to carbonyl compounds and alkynes to ynones using in situ-generated peroxides.
Demonstrated catalytic alkane carboxylation with carbon monoxide, nitration with nitrogen dioxide, sulfonation with sulfur dioxide, and carbon-carbon bond construction with alkenes.

Cite This Study

Ishii et al. (2001) studied this question.

synapsesocial.com/papers/6a7b4cec5968508e56f3f9ff https://doi.org/10.1002/1615-4169(200107)343:5<393::aid-adsc393>3.0.co;2-k

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