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February 1, 2001Journal of Biological ChemistryOpen Access

Binding of Thrombin to Glycoprotein Ib Accelerates the Hydrolysis of Par-1 on Intact Platelets

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Authors

ECErica De CandiaUniversità Cattolica del Sacro CuoreSHScott W. HallStanford UniversitySRSergio RutellaNottingham Trent University

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Candia et al. (2001) studied this question.

synapsesocial.com/papers/6a7b4fbe14b028facf0ec526https://doi.org/10.1074/jbc.m008160200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1“Clotspeed,” a mathematical simulation of the functional properties of prothrombinase.1984 · 138 citations
  2. 2Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling.1994 · 145 citations
  3. 3Contributions of Glycoprotein Ib and the Seven Transmembrane Domain Receptor to Increases in Platelet Cytoplasmic [Ca2+] Induced by α-Thrombin1996 · 67 citations
  4. 4Crystallographic Structures of Thrombin Complexed with Thrombin Receptor Peptides: Existence of Expected and Novel Binding Modes1994 · 158 citations
  5. 5Thrombin Interacts with Thrombomodulin, Protein C, and Thrombin-activatable Fibrinolysis Inhibitor via Specific and Distinct Domains1999 · 99 citations