Why the study?
Are positive anti-CCP antibodies associated with an increased risk of ischemic heart disease in patients with rheumatoid arthritis?
Population
937 patients with a diagnosis of rheumatoid arthritis (RA)
Comparison
Positive anti-cyclic citrullinated peptide… vs Negative anti-CCP antibodies
Design
Cohort
Authors
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Anti-CCP positivity was independently associated with higher IHD risk in RA; hypothesis-generating for targeted CV strategies pending prospective validation.
Are positive anti-CCP antibodies associated with an increased risk of ischemic heart disease in patients with rheumatoid arthritis?
In patients with rheumatoid arthritis, the presence of anti-CCP antibodies is independently associated with a higher risk of ischemic heart disease and mortality, independent of traditional cardiovascular risk factors.
López‐Longo et al. (2009) studied this question.
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