Key result
Diuretics remain essential for managing hypertension and hypervolemia, with data showing chlorthalidone lowers cardiovascular events by one-fifth compared to hydrochlorothiazide.
Why the study?
Do diuretics reduce cardiovascular events and mortality in patients with hypertension and heart failure?
Population
Patients with hypertension, hypervolemia, congestive heart failure, and post-acute myocardial infarction
Comparison
Diuretics vs Placebo, other antihypertensive classes, or…
Design
Review
Authors
Loading...
Supports diuretic use in hypertension and HF; leaves open optimal agent selection in prospective trials.
Do diuretics reduce cardiovascular events and mortality in patients with hypertension and heart failure?
Diuretics remain a diverse and highly effective class of medications for reducing cardiovascular events and mortality in hypertension and heart failure.
Roush et al. (2013) conducted a review in Hypertension, hypervolemia, and electrolyte disorders. Diuretics vs. Placebo, other antihypertensives, or other diuretics was evaluated. Diuretics remain essential for managing hypertension and hypervolemia, with data showing chlorthalidone lowers cardiovascular events by one-fifth compared to hydrochlorothiazide.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: