January 1, 1984AJP Regulatory Integrative and Comparative Physiology

Differential renal and splenic nerve responses to vagal and spinal afferent inputs

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Population

Anesthetized, sinoaortic-denervated cats in which upper thoracic sympathetic ganglia had been removed

Design

Preclinical

Authors

LWLynne C. WeaverWestern University HFHildburg FryFederal Institute for Risk Assessment RMR. L. MecklerThe University of Queensland

Discussion

Member takes

Implication

Animal data show selective sympathetic outflow to kidney and spleen; hypothesis-generating and should not change clinical practice.

Structured PICO

Population

Anesthetized, sinoaortic-denervated cats in which upper thoracic sympathetic ganglia had been removed

Intervention

Stimulation of vagally innervated cardiac receptors and receptors of abdominal visceral and muscle spinal afferent nerves (via left atrial injections of veratridine or bradykinin, abdominal aorta injections of bradykinin, and visceral ischemia/mesenteric stretch)

Outcome

Renal and splenic nerve dischargessurrogate

Sympathetic control of the kidney and spleen can be selective, demonstrating significant discreteness of sympathetic outflow to the viscera.

Cite This Study

Weaver et al. (1984) studied this question.

synapsesocial.com/papers/6a7b7ebf756812e3958a0795 https://doi.org/10.1152/ajpregu.1984.246.1.r78

View Full Paper

Ask AI

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Differential renal and splenic nerve responses to vagal and spinal afferent inputs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Differential renal and splenic nerve responses to vagal and spinal afferent inputs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider