Interdependence of Variability of the Heart Rhythm With Daily Profile of Arterial Pressure in Patients With Arterial Hypertension

The article analyzes the interrelation of the heart rate variability with the daily profile of arterial pressure in patients with arterial hypertension.Objective: to study the relationship between heart variability indices the daily profile of blood pressure in patients with arterial hypertension I-II stage.Material and methods. A survey of 145 patients with stage I and II hypertension, aged 29 to 53 years old (average age - 46.75 ± 0.56 years) was performed. According to a result of 24-hour daily blood pressure monitoring, all patients were divided into 3 groups: 62 patients with normal blood pressure decrease at night (dippers); 67 patients with insufficient decrease in blood pressure at night (non-dipper); 16 patients with excessive nightly decrease in blood pressure (over-dipper).Results: under background conditions patients with an insufficient (non-dipper) or surplus (over-dipper) decline HELL at night were characterized by less general power of spectrum (ТР) and VLF of modulations. In addition, substantial increase of sympatic trend in (non-dipper) and parasympathetic trend in (over-dipper) attracts attention. Thus, LF part of vibrations of LF% in the group of patients of "non-dipper" made 35,34±2,25%, and significantly exceeded the value of analogical index in the group of "dipper" (22,75±1,15%, p <0,01), but the part of HF of vibrations of HF% in the group of patients of "over-dipper", having made 32,96±1,18%, significantly exceeded the value for an analogical index in the group of "dipper" (14,92±0,95%, p <0,01) and "non-dipper" (17,43±1,12%,p <0,02). Non-dipper were characterized by the least values of cute modulations and index of sympatho-vagal balance (p <0,01).Conclusion. It has been established that, the inherent vegetative maintenance of cardiac activity was preserved for the patients in the category of dipper and overdipper. At the same time, patients who have a daily profile of overseas dippery type, are characterized by adequate functioning of the sympathetic department of the autonomic nervous system against a background of high activity of the parasympathetic link. Patients who belong to the non-dipper category show a decrease in the adaptive capacity of the sympathetic nervous system against a background of hyperparasympathicotonia in a state of rest and an adequate response to parasympathetic modulation during the loading test.