Key result
PIVOT MRI demonstrated that patients with peripheral artery disease had a blunted and delayed hyperemic response compared with healthy controls, which correlated with disease severity.
Why the study?
Does the PIVOT MRI technique detect differences in temporal dynamics of blood flow and oxygen saturation between patients with peripheral artery disease and healthy controls?
Population
96 patients with peripheral artery disease of varying severity and 10 healthy controls
Comparison
Perfusion, Intravascular Venous Oxygen… vs 10 healthy controls
Design
Cross-sectional
Authors
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May facilitate noninvasive PAD severity assessment; hypothesis-generating for clinical adoption.
Observational (n=106)
Does the PIVOT MRI technique detect differences in temporal dynamics of blood flow and oxygen saturation between patients with peripheral artery disease and healthy controls?
The PIVOT MRI technique effectively quantifies delayed and blunted hyperemic responses in PAD patients, correlating with disease severity.
Englund et al. (2015) conducted an observational in peripheral artery disease (n=106). Perfusion, Intravascular Venous Oxygen saturation, and T2* (PIVOT) MRI vs. Healthy controls was evaluated on Temporal dynamics of blood flow and oxygen saturation during reactive hyperemia. PIVOT MRI demonstrated that patients with peripheral artery disease had a blunted and delayed hyperemic response compared with healthy controls, which correlated with disease severity.
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