Key result
Treatment with emergency cesarean section, aggressive hydration, fenofibrate, and gemfibrozil led to a successful recovery in a pregnant woman with hypertriglyceridemia-induced acute pancreatitis.
Why the study?
Hypertriglyceridemia is a rare cause of acute pancreatitis in pregnancy and an aggravating factor of severe disease, warranting improved early recognition and treatment strategies.
Case Report (n=1)
Aggressive medical management including lipid-lowering agents and emergency delivery can lead to successful recovery in severe hypertriglyceridemia-induced acute pancreatitis during pregnancy.
May support emergency cesarean plus lipid-lowering therapy in hypertriglyceridemia-induced pancreatitis in pregnancy; hypothesis-generating from single case.
OBJECTIVE: Hypertriglyceridemia (HTG) is a rare cause of acute pancreatitis (AP) in pregnancies and has emerged as an aggravating factor of severe pancreatitis. To enhance the diagnosis and management of HTG-induced AP during pregnancy by improving early recognition, optimizing treatment strategies, and minimizing maternal and fetal complications. CASE REPORT: This is a 29-year-old multigravida woman at a gestational age of 34 weeks and 2 days who presented with sudden abdominal pain and vomiting. She had severe hypertriglyceridemia (7855 mg/dL) and was diagnosed with acute pancreatitis. After an emergency cesarean section, the patient received aggressive hydration, as well as fenofibrate and gemfibrozil as lipid-lowering agents, along with other supportive care. This treatment led to a successful recovery. CONCLUSION: The management of HTG-induced AP must consider both maternal and fetal health, with options such as lipid-lowering agents and plasmapheresis being explored, further research was required to ascertain their safety during pregnancy.
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Huang et al. (2025) conducted a case report in Hypertriglyceridemia-induced acute pancreatitis (n=1). Emergency cesarean section, hydration, and lipid-lowering agents (fenofibrate and gemfibrozil) was evaluated on Recovery. Treatment with emergency cesarean section, aggressive hydration, fenofibrate, and gemfibrozil led to a successful recovery in a pregnant woman with hypertriglyceridemia-induced acute pancreatitis.
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