Key result
Partial surgical tumor resection followed by chemotherapy and radiotherapy was utilized to manage a large primary leiomyosarcoma in the inferior vena cava extending to the right atrium.
Case Report (n=323)
Primary leiomyosarcoma of the inferior vena cava extending to the right atrium is a rare condition where partial resection and chemoradiotherapy can be utilized to prevent circulatory collapse and pulmonary embolization.
Partial resection with doxorubicin-radiotherapy may avert acute embolization in right atrial leiomyosarcoma; leaves open optimal multimodal strategies for this rare entity.
A 38-year-old woman had developed an abdominal distention, lower extremity edema, and dyspnea. Imaging examination revealed a large mass in the right atrium which was connected to lesions within the inferior vena cava. Although complete resection of the mass was not possible, partial surgical tumor resection was performed to avoid pulmonary embolization and circulatory collapse. Leiomyosarcoma was diagnosed histologically, and chemotherapy (doxorubicin) followed by radiotherapy was started. By reviewing papers published in the past 10 years that included 322 patients, we also discuss the clinical presentations and prognosis of leiomyosarcoma in the inferior vena cava.
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Fujita et al. (2016) conducted a case report in Primary Leiomyosarcoma in the Inferior Vena Cava (n=323). Partial surgical tumor resection, chemotherapy (doxorubicin), and radiotherapy was evaluated. Partial surgical tumor resection followed by chemotherapy and radiotherapy was utilized to manage a large primary leiomyosarcoma in the inferior vena cava extending to the right atrium.
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