Key result
Chemotherapy, particularly anthracyclines and trastuzumab, induces right ventricular structural, functional, and mechanical impairment through various complex mechanisms.
Why the study?
Does chemotherapy (anthracyclines and trastuzumab) induce right ventricular structural, functional, and mechanical changes?
Population
Patients treated with chemotherapy, specifically protocols involving anthracyclines and trastuzumab
Design
Review
Authors
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RV effects of chemotherapy merit monitoring in cardio-oncology; leaves open prospective trials for clinical impact.
Does chemotherapy (anthracyclines and trastuzumab) induce right ventricular structural, functional, and mechanical changes?
Chemotherapy-induced cardiac toxicity affects the right ventricle simultaneously with the left ventricle, highlighting the need for comprehensive biventricular assessment in cardio-oncology.
Tadić et al. (2017) conducted a review in Chemotherapy-induced cardiovascular complications. Chemotherapy was evaluated on Right ventricular (RV) remodeling. Chemotherapy, particularly anthracyclines and trastuzumab, induces right ventricular structural, functional, and mechanical impairment through various complex mechanisms.
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