Why the study?
Does local cooling reduce cutaneous vascular conductance through nitric oxide synthase inhibition and adrenergic mechanisms in humans?
Population
8 human subjects (6 male, 2 female)
Comparison
Local cooling for 35 min with local… vs Control sites or sites with different…
Design
Other
Authors
Loading...
Identifies noradrenergic and NOS mediation of cooling vasoconstriction; extends mechanistic understanding but leaves clinical translation open.
Does local cooling reduce cutaneous vascular conductance through nitric oxide synthase inhibition and adrenergic mechanisms in humans?
The cutaneous vasoconstrictor response to slow local cooling is mediated by a combination of increased noradrenaline release and decreased activity of nitric oxide synthase and downstream processes.
Hodges et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: