Why the study?
Does taking aspirin and clopidogrel up to 2 days prior to CABG increase postoperative drainage loss in patients undergoing CABG?
Population
261 patients undergoing coronary artery bypass graft surgery (CABG)
Comparison
Aspirin and clopidogrel taken up to 1 or 2 days… vs No anti-platelet medication prior to surgery
Design
Cohort
Follow-up
5 days after the operation
Authors
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May warrant earlier DAPT cessation before CABG to limit bleeding; leaves optimal timing open for randomized confirmation.
Does taking aspirin and clopidogrel up to 2 days prior to CABG increase postoperative drainage loss in patients undergoing CABG?
Continuing aspirin and clopidogrel up to 2 days prior to CABG surgery is associated with significantly increased postoperative blood loss.
Heymann et al. (2005) studied this question.
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