Key result
Frailty was associated with a nearly threefold increased odds of 30-day mortality (OR 2.91) compared to non-frail patients among adults aged 65 years and older undergoing emergency general surgery.
Why the study?
The study was conducted to determine the association between frailty and mortality among adults ≥ 65 years old undergoing emergency general surgery.
Does frailty increase mortality in adults ≥ 65 years old undergoing emergency general surgery?
Population
1289 adults ≥ 65 years old undergoing emergency general surgery across six cohort studies
Comparison
Frail vs non-frail patients
Design
Systematic review and random-effects meta-analysis
Authors
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Frailty screening may aid risk stratification in older EGS patients; leaves open whether interventions improve outcomes.
Meta-Analysis (n=1,289)
Does frailty increase mortality in adults ≥ 65 years old undergoing emergency general surgery?
Odds Ratio: 2.91 (95% CI 2–4.23)
Frailty is significantly associated with increased 30-day mortality and worse secondary outcomes in older adults undergoing emergency general surgery.
Fehlmann et al. (2021) conducted a meta-analysis in Emergency general surgery (n=1,289). Frailty vs. Non-frail was evaluated on 30-day mortality (OR 2.91, 95% CI 2.00-4.23). Frailty was associated with a nearly threefold increased odds of 30-day mortality (OR 2.91) compared to non-frail patients among adults aged 65 years and older undergoing emergency general surgery.