Key result
Patients living with frailty have a significantly higher chance of dying within 30 days after an emergency surgical admission compared to non-frail patients (OR 1.99).
Why the study?
The use of frailty has extended into surgery, prompting an evaluation of its association with mortality, length of hospital stay, and 30-day readmission in emergency surgical patients.
Does frailty increase mortality, length of hospital stay, and readmission in emergency surgical patients?
Population
562.070 participants across 21 studies from 8 countries
Comparison
Patients living with frailty vs non-frail patients
Design
Systematic review and meta-analysis of prospective or retrospective cohorts
Authors
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Frailty signals higher 30-day mortality risk after emergency surgery; supports prognostic assessment yet leaves open whether interventions improve outcomes.
Meta-Analysis (n=562,070)
Does frailty increase mortality, length of hospital stay, and readmission in emergency surgical patients?
Odds Ratio: 1.99 (95% CI 1.76–2.21)
p-value: p=<0.001
Frailty is significantly associated with increased short-term mortality, longer hospital stays, and higher 30-day readmission rates in patients undergoing emergency surgery.
Leiner et al. (2022) conducted a meta-analysis in Emergency surgery (n=562,070). Frailty vs. Non-frail patients was evaluated on 30-day mortality (OR 1.99, 95% CI 1.76-2.21, p=<0.001). Patients living with frailty have a significantly higher chance of dying within 30 days after an emergency surgical admission compared to non-frail patients (OR 1.99).
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