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January 1, 2012Neuroepidemiology

Women aged 35-84 years had a lower incidence of first stroke hospitalization than men, but women aged ≥85 years had a significantly higher 30-day case fatality (RR 1.14; 95% CI 1.05-1.23).

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Why the study?

Does sex affect the incidence and 30-day case fatality of first stroke hospitalization across different age groups?

Population

Patients with first hospitalization for stroke in Hong Kong between 2000 and 2007

Comparison

Female sex vs Male sex

Design

Cohort

Follow-up

30 days

Key result

Women aged 35-84 years had a lower incidence of first stroke hospitalization than men, but women aged ≥85 years had a significantly higher 30-day case fatality (RR 1.14; 95% CI 1.05-1.23).

Authors

SWShenghui WuSHShu‐Chuan HoPCPui Hing Chau

Discussion

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Member takes

Overview

Supports age-stratified sex differences in stroke outcomes; extends observational data but leaves open mechanisms and targeted interventions.

Study Design

Type

Observational

Multicenter

Yes

Structured PICO

Does sex affect the incidence and 30-day case fatality of first stroke hospitalization across different age groups?

P
Population
Patients with first hospitalizations for stroke in Hong Kong between 2000 and 2007, analyzed to explore sex differences in incidence and mortality across age groups.
E
Exposure
Female sex
C
Comparator
Male sex
O
Outcome
Incidence of first hospitalization for stroke and 30-day case fatalityhard clinical

Main Result

Relative Risk: 1.14 (95% CI 1.05–1.23)

Women under 85 have a lower incidence of stroke than men, but women 85 and older face a higher 30-day case fatality rate.

Cite This Study

Wu et al. (2012) conducted an observational in Stroke. Female sex vs. Male sex was evaluated on 30-day case fatality (ages ≥85 years) (RR 1.14, 95% CI 1.05-1.23). Women aged 35-84 years had a lower incidence of first stroke hospitalization than men, but women aged ≥85 years had a significantly higher 30-day case fatality (RR 1.14; 95% CI 1.05-1.23).

synapsesocial.com/papers/6a7bc54b073f483584df8f55https://doi.org/10.1159/000335040
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sex Differences in Incidence, Mortality, and Survival in Individuals With Stroke in Scotland, 1986 to 20052009 · 83 citations
  2. 2Trends in ischaemic heart disease hospitalisation and case fatality in the Hong Kong Chinese population 2000–2009: a secondary analysis2013 · 5 citations
  3. 3Trends in Stroke Incidence in Hong Kong Differ by Stroke Subtype2010 · 57 citations
  4. 4Sex differences in coronary heart disease and stroke mortality: a global assessment of the effect of ageing between 1980 and 20102017 · 491 citations
  5. 5Stroke Hospitalizations Over Three Decades: Lower for Men, Unchanged for Women. A Population-Based Study2014 · 7 citations