Why the study?
What is the frequency and what are the risk factors of neuroleptic malignant syndrome in psychiatric inpatients treated with neuroleptic agents?
Population
78,708 inpatients treated with neuroleptic agents in a major psychiatric hospital (1,510 beds) in Moscow
Design
Cohort
Follow-up
10 years
Authors
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Low NMS frequency with notable mortality warrants vigilance in young inpatients; leaves open causal role of age pending prospective validation.
What is the frequency and what are the risk factors of neuroleptic malignant syndrome in psychiatric inpatients treated with neuroleptic agents?
The frequency of neuroleptic malignant syndrome in a large Russian psychiatric hospital was very low (0.02%), with young age identified as a significant risk factor.
Спивак et al. (2000) studied this question.
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