Population
Isolated perfused rat hearts
Design
Preclinical
Authors
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No immediate clinical implications from rat heart data; leaves open whether Fru-2,6-P2 control extends to human cardiac metabolism.
In isolated rat hearts, cardiac phosphofructokinase and glycolysis are controlled by the availability of Fru-6-P and Fru-2,6-P2 rather than by citrate or adenine nucleotides.
Lawson et al. (1987) studied this question.
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