July 1, 2001Epidemiology
Increased Risks of Circulatory Diseases in Late Pregnancy and Puerperium
Why the study?
Does late pregnancy and puerperium increase the risk of circulatory diseases compared to nonpregnant and early pregnant states?
Population
654,957 women who had 1,003,489 deliveries from 1987 through September 1995 in a nationwide Swedish cohort
Comparison
Late pregnancy and puerperium vs Unexposed (nonpregnant and early pregnant) women
Design
Cohort
Follow-up
From 1987 through September 1995
Authors
Discussion
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Member takes
Implication
Heightens peripartum VTE vigilance; leaves open prospective prevention trials.
Structured PICO
Does late pregnancy and puerperium increase the risk of circulatory diseases compared to nonpregnant and early pregnant states?
P
Population
654,957 women who had 1,003,489 deliveries from 1987 through September 1995 in a nationwide Swedish cohort
I
Intervention
Late pregnancy (third trimester) and puerperium (around delivery and up to 6 weeks postpartum)
C
Comparator
Unexposed (nonpregnant and early pregnant) women
O
Outcome
Incidence of circulatory diseases (venous thrombosis, pulmonary embolism, subarachnoid hemorrhage, intracerebral hemorrhage, cerebral infarction, and myocardial infarction)hard clinical
The risk of circulatory diseases, including venous thrombosis and pulmonary embolism, is dramatically increased around the time of delivery and remains elevated during the first 6 weeks postpartum.
Cite This Study
Ros et al. (2001) studied this question.