Key result
Postoperative VTE prophylaxis with aspirin was associated with a VTE rate of 2.9% compared to 10.3% with non-aspirin prophylaxis in patients undergoing orthopaedic oncologic surgery.
Why the study?
Does aspirin prevent venous thromboembolism in patients undergoing orthopaedic oncologic surgery compared to non-aspirin prophylaxis?
Population
130 patients diagnosed with a primary malignant soft-tissue or bone tumor or metastatic carcinoma.
Comparison
Aspirin for postoperative VTE prophylaxis vs Non-aspirin VTE prophylaxis
Design
Cohort
Authors
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Aspirin appeared effective for VTE prophylaxis in this cohort; leaves open need for prospective randomized confirmation before practice change.
Cohort (n=130)
Does aspirin prevent venous thromboembolism in patients undergoing orthopaedic oncologic surgery compared to non-aspirin prophylaxis?
Absolute Event Rate: 2.9% vs 10.3%
Aspirin may be an effective option for VTE chemoprophylaxis in patients undergoing orthopaedic oncologic surgery, with a VTE rate of 2.9% compared to 10.3% with non-aspirin prophylaxis.
Mendez et al. (2017) conducted a cohort in Orthopaedic oncologic surgery (n=130). Aspirin vs. Non-aspirin prophylaxis was evaluated on Venous thromboembolism (VTE). Postoperative VTE prophylaxis with aspirin was associated with a VTE rate of 2.9% compared to 10.3% with non-aspirin prophylaxis in patients undergoing orthopaedic oncologic surgery.
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