What question did this study set out to answer?

To compare the efficacy of a new collagen matrix prototype against the traditional free connective tissue graft for augmenting keratinized gingiva or mucosa around fixed prosthetic restorations.

August 12, 2009Journal Of Clinical PeriodontologyOpen Access

Clinical evaluation of a new collagen matrix (Mucograft® prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial

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Authors

MSMariano SanzBritish Society of Periodontology RLRamón LorenzoSociedad Española de Periodoncia y Osteointegración JAJuan José ArandaUniversidad Complutense de Madrid

Discussion

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Implication

Randomized trial demonstrates equivalent keratinized tissue gains with lower morbidity for a collagen matrix in patients with dental restorations, indicating a less invasive grafting alternative.

Key Points

To compare the efficacy of a new collagen matrix prototype against the traditional free connective tissue graft for augmenting keratinized gingiva or mucosa around fixed prosthetic restorations.
Conducted a randomized, longitudinal, parallel controlled clinical trial in 20 patients presenting with at least one site with minimal keratinized tissue (≤ 1 mm).
Assessed the primary endpoint of keratinized tissue width at 6 months, alongside secondary outcomes including aesthetic appearance, periodontal health parameters, and patient morbidity at baseline, 1, 3, and 6 months.
At 6 months, the mean width of keratinized tissue increased to 2.5 (0.9) mm in the collagen matrix group and 2.6 (0.9) mm in the connective tissue graft group, with no significant difference between arms.
Both treatments showed marked graft tissue contraction over 6 months (67% in the collagen matrix group versus 60% in the connective tissue graft group) while maintaining stable periodontal health parameters.
The collagen matrix procedure resulted in significantly lower patient morbidity, measured by reduced pain scores and analgesic consumption, alongside shorter surgical operative times.

Cite This Study

Sanz et al. (2009) studied this question.

synapsesocial.com/papers/6a7be733d27879525375fa78 https://doi.org/10.1111/j.1600-051x.2009.01460.x

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Implication

Randomized trial demonstrates equivalent keratinized tissue gains with lower morbidity for a collagen matrix in patients with dental restorations, indicating a less invasive grafting alternative.

Clinical evaluation of a new collagen matrix (Mucograft® prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinical evaluation of a new collagen matrix (Mucograft® prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial

Discussion

Member takes

Implication

Key Points

Cite This Study

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