Why the study?
Does status epilepticus produce chronic alterations in cardiac sympathovagal balance in Sprague-Dawley rats?
Does status epilepticus produce chronic alterations in cardiac sympathovagal balance in Sprague-Dawley rats?
Status epilepticus causes chronic autonomic dysregulation characterized by sympathetic dominance and decreased vagal tone, which may contribute to post-seizure cardiac mortality.
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May link status epilepticus to autonomic cardiac risk in models; leaves open human translation.
Metcalf et al. (2008) studied this question.