Why the study?
Does fluvastatin improve aortic compliance, coronary calcification, and carotid intimal-medial thickness in hypercholesterolaemic patients?
Population
64 hypercholesterolaemic patients, 24 with and 40 without coronary artery disease
Design
Cohort
Follow-up
1 year
Authors
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Fluvastatin-associated vascular surrogate improvements should not change practice; hypothesis-generating and requires RCT confirmation.
Does fluvastatin improve aortic compliance, coronary calcification, and carotid intimal-medial thickness in hypercholesterolaemic patients?
Fluvastatin therapy for 1 year improves surrogate markers of vascular health, including aortic compliance and carotid intimal-medial thickness, in hypercholesterolemic patients.
Forbat et al. (1998) studied this question.
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