Why the study?
The study was designed to test whether the arterial baroreflex is involved in causing patterned, region-specific shifts in sympathetic nerve activity and heart rate during freezing behaviour in conscious rats.
Population
Male Wistar rats chronically instrumented with electrodes and catheters
Comparison
Freezing behaviour induced by loud white noise vs 60-min control period
Design
Preclinical physiological study
Authors
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Hypothesis-generating for discrete baroreflex modulation of sympathetic activity; leaves open translation to human cardiovascular responses.
Freezing behavior in rats induces regionally specific shifts in baroreflex control of sympathetic nerve activity and heart rate, indicating discrete separation of baroreflex pathways.
Kondo et al. (2021) studied this question.
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