Why the study?
Does statin therapy reduce albuminuria or proteinuria compared to placebo?
Population
15 randomized, placebo-controlled trials pooling 1,384 patients with baseline and follow-up measurements of…
Comparison
Statins as a class vs Placebo
Design
Meta-analysis
Follow-up
average 24 weeks
Authors
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Supports statin consideration for albuminuria reduction in proteinuric patients; reinforces renoprotective effects in Level 1 meta-analysis.
Does statin therapy reduce albuminuria or proteinuria compared to placebo?
Statin therapy significantly reduces pathologic albuminuria and proteinuria, particularly in patients with baseline excretion greater than 30 mg/d.
Douglas et al. (2006) studied this question.
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