January 1, 2012Hip International

Direct Thrombin Inhibitor (Dti) vs. Aspirin in Primary Total Hip and Knee Replacement Using Wound Ooze as the Primary Outcome Measure. A Prospective Cohort Study

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Why the study?

Does direct thrombin inhibitor increase wound ooze compared to aspirin in patients undergoing primary total hip and knee replacement?

Structured PICO

Does direct thrombin inhibitor increase wound ooze compared to aspirin in patients undergoing primary total hip and knee replacement?

Population

110 patients undergoing primary total hip replacement (THR) and total knee replacement (TKR)

Intervention

Direct thrombin inhibitor (DTI)

Comparator

Aspirin

Outcome

Wound ooze (mean days to dryness)safety

Direct thrombin inhibitors significantly increase the duration of postoperative wound ooze compared to aspirin in patients undergoing lower-limb arthroplasty.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May favor aspirin to limit ooze after arthroplasty; hypothesis-generating pending RCTs.

Cite This Study

Aquilina et al. (2012) studied this question.

synapsesocial.com/papers/6a7c080b48312d37e475fd4e https://doi.org/10.5301/hip.2012.9058

View Full Paper

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Direct Thrombin Inhibitor (Dti) vs. Aspirin in Primary Total Hip and Knee Replacement Using Wound Ooze as the Primary Outcome Measure. A Prospective Cohort Study

Structured PICO

Discussion

Implication

Cite This Study

Direct Thrombin Inhibitor (Dti) vs. Aspirin in Primary Total Hip and Knee Replacement Using Wound Ooze as the Primary Outcome Measure. A Prospective Cohort Study

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider