Why the study?
Does skeletal muscle atrophy limit maximal exercise capacity in stable ambulatory patients with heart failure?
Does skeletal muscle atrophy limit maximal exercise capacity in stable ambulatory patients with heart failure?
Exercise intolerance in stable ambulatory patients with heart failure is not due to skeletal muscle atrophy, despite a correlation between leg lean mass and VO2peak.
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Exercise intolerance in ambulatory HF unlikely due to atrophy; hypothesis-generating for leg lean mass-VO2peak link.
Lang et al. (1997) studied this question.
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