January 1, 1985Clinical and Experimental Hypertension
Reproducibility of Blood Pressure Values in Normotensive Subjects
Why the study?
Is 24-hour ambulatory blood pressure monitoring reproducible in normotensive subjects?
Population
56 normal volunteers (normotensive subjects)
Design
Cohort
Follow-up
Two separate 24-hour periods
Authors
Discussion
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Implication
Supports reproducibility of ambulatory BP monitoring in normotensives; leaves open generalizability to hypertensives and clinical decision-making.
Key Points
- To assess the day-to-day reproducibility of whole-day and interval ambulatory blood pressure averages in healthy, normotensive individuals.
- Monitored 56 normal volunteers across two separate 24-hour study days.
- Recorded blood pressure at 7.5-minute intervals using an automated, non-invasive ambulatory monitoring device.
- Whole-day systolic blood pressure averages were 119 ± 10 mm Hg on day one and 117 ± 11 mm Hg on day two, with differences exceeding 10 mm Hg observed in 10 subjects.
- Whole-day diastolic blood pressure averages were 75 ± 7 mm Hg on day one and 73 ± 8 mm Hg on day two, with differences exceeding 5 mm Hg observed in 15 subjects.
- High consistency between study days was also maintained during shorter intervals, including a 2-hour morning window (8 AM to 10 AM), daytime (6 AM to 10 PM), and nighttime (10 PM to 6 AM).
Structured PICO
Is 24-hour ambulatory blood pressure monitoring reproducible in normotensive subjects?
P
Population
56 normal volunteers (normotensive subjects)
I
Intervention
24-hour ambulatory blood pressure monitoring using a non-invasive automatic device measuring BP at 7.5 minute intervals on two separate study days
O
Outcome
Reproducibility of whole-day systolic and diastolic blood pressure averagessurrogate
Non-invasive ambulatory blood pressure monitoring yields reproducible values across whole-day and shorter time periods in normotensive individuals.
Cite This Study
Drayer et al. (1985) studied this question.