December 1, 1980Clinical Science
Ambulant Blood Pressure: Reproducibility and the Assessment of Interventions
Key result
Intra-arterial blood pressure monitoring over 48 hours in 17 patients showed no significant day-to-day differences in hourly mean values except after administration of a hypotensive agent.
Why the study?
Is intra-arterial blood pressure monitoring reproducible day-to-day in freely ambulant hypertensive patients?
Population
17 freely ambulant hypertensive patients
Comparison
Single dose of a hypotensive agent before… vs No change of therapeutic regimen throughout (n=8)
Design
Cohort
Follow-up
48 hours
Authors
Discussion
Loading...
Member takes
Implication
Supports reliable ambulatory BP assessment in hypertension; leaves open longer-term variability and therapy effects.
Key Points
- The study aims to evaluate the day-to-day reproducibility of intra-arterial blood pressure in ambulant hypertensive patients.
- Monitored 17 hypertensive patients for 48 hours, allowing normal daily routines.
- Eight patients maintained their therapeutic regimen; nine took a hypotensive agent before the second night.
- Analyzed hourly mean heart rate, systolic, and diastolic blood pressure.
- No significant difference in blood pressure readings between the first and second day, except after intervention in the second group.
- Variation in measurements reflects normal daily activities of subjects.
- Reliable assessment of therapeutic interventions demonstrated through pooled measurements.
Study Design
Type
Observational (n=17)
Structured PICO
Is intra-arterial blood pressure monitoring reproducible day-to-day in freely ambulant hypertensive patients?
P
Population
17 freely ambulant hypertensive patients monitored for 48 hours to assess day-to-day reproducibility of intra-arterial blood pressure.
E
Exposure
Single dose of a hypotensive agent before retiring on the second night (n=9)
C
Comparator
No change of therapeutic regimen throughout (n=8)
O
Outcome
Day-to-day reproducibility of hourly mean values of heart rate, systolic and diastolic blood pressuresurrogate
Intra-arterial blood pressure monitoring over 48 hours shows good day-to-day reproducibility, enabling reliable assessment of therapeutic interventions in small groups.
Limitations
- Allowing subjects to follow their normal daily routine produces inevitable variation in their pattern of physical and other activity.
Cite This Study
Mann et al. (1980) conducted an observational in Hypertension (n=17). Single dose of a hypotensive agent vs. No change of therapeutic regimen was evaluated on Day-to-day reproducibility of intra-arterial blood pressure (hourly mean values of heart rate, systolic and diastolic blood pressure). Intra-arterial blood pressure monitoring over 48 hours in 17 patients showed no significant day-to-day differences in hourly mean values except after administration of a hypotensive agent.