What question did this study set out to answer?

To evaluate the reproducibility of ambulatory blood pressure levels, blood pressure variability, and treatment-induced blood pressure reduction in patients with hypertension.

March 23, 2010Journal of Hypertension

Reproducibility of ambulatory blood pressure in treated and untreated hypertensive patients

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Why the study?

Is ambulatory blood pressure monitoring reproducible in treated and untreated hypertensive patients?

Key Points

To evaluate the reproducibility of ambulatory blood pressure levels, blood pressure variability, and treatment-induced blood pressure reduction in patients with hypertension.
Enrolled 42 hypertensive patients who underwent 24-hour ambulatory blood pressure monitoring four times: twice before initiating treatment and twice after treatment.
Calculated blood pressure variability using standard deviation, weighted standard deviation, coefficient of variation, and average real variability, while defining morning surge via diaries or actigraphy.
Evaluated measurement repeatability using repeatability coefficients and Bland-Altman analysis.
Awake, asleep, 24-hour, and morning blood pressure values, as well as all four blood pressure variability measures, showed strong agreement between repeat monitoring sessions across both treatment periods.
Morning blood pressure surge reproducibility was poor when calculated using self-reported diary entries, but correspondence improved when calculated using objective actigraphy data.
The reproducibility of blood pressure reduction was fair for single blood pressure parameters, confirming that a single 24-hour recording before and after treatment is sufficient to evaluate drug efficacy.

Structured PICO

Is ambulatory blood pressure monitoring reproducible in treated and untreated hypertensive patients?

Population

42 hypertensive patients

Intervention

Ambulatory blood pressure monitoring (ABPM) performed four times (twice before and twice after treatment)

Outcome

Reproducibility of ambulatory blood pressure (ABP), BP variability, and BP reductionsurrogate

Ambulatory blood pressure monitoring shows good reproducibility for ABP levels and variability, supporting the use of single ABPM sessions before and after treatment to assess drug efficacy.

Discussion

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Implication

ABPM reproducibility appears high for levels and variability in hypertensives; extends observational data but leaves open randomized confirmation before practice change.

Cite This Study

Hoshide et al. (2010) studied this question.

synapsesocial.com/papers/6a7d66be8253d2b493a004f6 https://doi.org/10.1097/hjh.0b013e3283378477

Topics

Hypertension management

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Implication

ABPM reproducibility appears high for levels and variability in hypertensives; extends observational data but leaves open randomized confirmation before practice change.

Reproducibility of ambulatory blood pressure in treated and untreated hypertensive patients

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Reproducibility of ambulatory blood pressure in treated and untreated hypertensive patients

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

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