Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 1988Cell Structure and FunctionOpen Access

A novel 53kDa actin binding protein from porcine brain - Further biochemical and immunological characterization.

View Full Paper
Ask AI
Bookmark
Share

Population

Porcine brain extract, rat brain extract, HeLa cells, and BS-C-1 cells

Design

Preclinical

Authors

SMShohei MaékawaUniversity of North Carolina at Chapel HillKOKunihiro OhtaTokyo Woman's Christian UniversityHSHikoichi SakaiToyohashi University of Technology

Discussion

Loading...

Member takes

Implication

Does not support practice change; leaves open functional roles of actin-binding proteins in cytoskeletal dynamics.

Structured PICO

P
Population
Porcine brain extract, rat brain extract, HeLa cells, and BS-C-1 cells
I
Intervention
Biochemical and immunological characterization (purification, Scatchard plot analysis, competitive binding assays, immunoblot analysis, immunological localization)
O
Outcome
Characteristics of the 53 K actin binding protein (association constant, competitive binding, tissue and cellular localization)surrogate

The 53kDa actin-binding protein from porcine brain shares binding characteristics with fascin and filamin and is localized in granular structures within cells.

Cite This Study

Maékawa et al. (1988) studied this question.

synapsesocial.com/papers/6a7c3069d249c0c91c3bdbe2https://doi.org/10.1247/csf.13.373
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Purification and characterization of an F-actin-bundling 55-kilodalton protein from HeLa cells.1985 · 123 citations
  2. 2Cofilin, a protein in porcine brain that binds to actin filaments and inhibits their interactions with myosin and tropomyosin1984 · 317 citations
  3. 3An actin-depolymerizing protein (destrin) from porcine kidney. Its action on F-actin containing or lacking tropomyosin1985 · 101 citations
  4. 4Evidence for actin filament-microtubule interaction mediated by microtubule-associated proteins1978 · 347 citations
  5. 5Purification and characterization of GP-55, a protein associated with actin-based cytoplasmic gels derived from brain tissue.1985 · 9 citations