Key result
Propofol anesthesia in children under 3 years old showed a difference in decreased systolic pressure (P<0.001) compared to volatile anesthetics, with no serious adverse events.
Why the study?
Does propofol anesthesia by target-controlled infusion improve safety and efficacy compared to volatile anesthetics in children below 3 years of age undergoing surgery?
Population
218 children below 3 years of age who underwent surgery between September 2013 and December 2016, based in…
Comparison
Propofol anesthesia by target-controlled infusion vs Volatile anesthetics
Design
Cohort
Follow-up
perioperative period
Authors
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Requires careful hemodynamic monitoring with propofol in young children; leaves open whether target-controlled infusion improves safety over volatiles.
Observational (n=218)
Does propofol anesthesia by target-controlled infusion improve safety and efficacy compared to volatile anesthetics in children below 3 years of age undergoing surgery?
p-value: p=<0.001
Propofol anesthesia by target-controlled infusion appears safe and effective in children under 3 years of age, with no serious perioperative adverse events compared to volatile anesthetics.
Kang et al. (2018) conducted an observational in pediatric surgery (n=218). Propofol anesthesia vs. Volatile anesthetics was evaluated on decreased systolic pressure (p=<0.001). Propofol anesthesia in children under 3 years old showed a difference in decreased systolic pressure (P<0.001) compared to volatile anesthetics, with no serious adverse events.
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