Key result
Environmental surveillance of 155 sewage specimens from 14 Italian wastewater treatment plants detected rat hepevirus RNA in 43.9% of samples.
Why the study?
Emerging rat hepatitis E virus has been linked to human hepatitis, but its epidemiology and genetic variability had not been evaluated via environmental wastewater surveillance in an Italian hot spot.
Population
155 sewage specimens from 14 wastewater treatment plants in Abruzzo, Italy
Design
Environmental surveillance study
Authors
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Hypothesis-generating for rat hepevirus zoonotic potential; leaves open human transmission risks pending targeted studies.
Observational (n=155)
Yes
Rat hepatitis E virus is a significant component of the wastewater microbiota in Abruzzo, Italy, highlighting the need to investigate its potential burden in humans.
Palombieri et al. (2023) conducted an observational in Rat hepatitis E virus (RHEV) in wastewater (n=155). Wastewater surveillance for rat hepevirus was evaluated on Detection of rat hepevirus RNA. Environmental surveillance of 155 sewage specimens from 14 Italian wastewater treatment plants detected rat hepevirus RNA in 43.9% of samples.
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