Non-directional asymmetry of paired organs is attributed to developmental ‘noise’. The level of asymmetry is inversely correlated to the degree of developmental stability. Children affected with familial cleft lip ± cleft palate have an increased asymmetry of their dermatoglyphics and molar teeth. The action of polygenes with a quasi-continuous distribution is consistent with this observation.
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Adams et al. (1967) studied this question.
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