Key result
COVID-19 produces acute cardiac injury in 10-20% of mild cases and greater than 50-60% of severe cases, alongside other complications such as arrhythmias, heart failure, and shock.
Why the study?
The COVID-19 pandemic caused global tumult and overburdened national health systems, prompting a discussion of its cardiovascular implications and complications based on recently clustered data.
Answers are grounded in this paper and cite their sources.
COVID-19 is associated with significant cardiovascular complications including acute cardiac injury, arrhythmias, and heart failure, while current evidence does not support discontinuing renin-angiotensin system blockers.
PURPOSE OF REVIEW: The new pandemic of coronavirus disease-2019 (COVID-19) has produced a global tumult and has overburdened national health systems. We herein discuss the cardiovascular implications and complications of this pandemic analyzing the most recent data clustered over the last several months. RECENT FINDINGS: COVID-19 afflicts the cardiovascular system producing acute cardiac injury in 10-20% of cases with mild disease but in greater than 50-60% in severe cases, contributing to patients' demise. Other cardiovascular complications include arrhythmias, heart failure, pulmonary embolism and shock. Off-label therapies are being trialed with their own inherent cardiovascular risks, while supportive therapies currently dominate, until more specific and effective antiviral therapies and vaccinations become available. A controversial issue relates to the safety of drugs blocking the renin--angiotensin system as an angiotensin-converting enzyme (ACE) homologue, ACE2, serves as the receptor for viral entry into host cells. However, to-date, no harm has been proven for these drugs. SUMMARY: In the cardiovascular system, COVID-19 can induce acute cardiac injury, arrhythmias, heart failure, pulmonary embolism, shock and death, whereas anti-COVID therapies also confer serious cardiovascular side-effects. Ongoing extensive efforts focus on specific vaccines and antivirals. Meanwhile, cardiovascular risk factors and diseases should be jointly controlled according to current evidence-based guidelines.
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Manolis et al. (2020) conducted a review in COVID-19. COVID-19 was evaluated on Acute cardiac injury. COVID-19 produces acute cardiac injury in 10-20% of mild cases and greater than 50-60% of severe cases, alongside other complications such as arrhythmias, heart failure, and shock.
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